A teacher who cannot leave her students alone. The difference is that Misaki's ways to help her students are easily seen as helpful and caring while Queen's Classroom has more of a deeper and darker meaning.

Both has a girl with a terminal disease finding love. 1 Litre of Tears is more based on how the girl works through her sickness through her daily life and also finding love. Hidamari no Kanajo is more about the love relationship between the two and what it means to have a time limit on their relationship.