Color Rush 2 (2022)

I recommend this both drama because , Male lead and Female lead
try to solve problem
In one drama explosion and another student murder/suicide

First Season of Color Rush 2.
The cast is a bit different but you should watch it for context.
The main couple is different but we get to know the world setting.

Both series have protagonists with a specific form of supernatural disease where only a small number of people around the world suffer from this rare disease. Both series also contain the idea that only their soulmate can help them in this disease.