Matsuko opened the conversation by telling that Kanjani's Okura was worried about his condition, but Murakami reminded him that they had talked about it before. The first segment was investigating things various things that people had to give up which included a man who was asked to give up drinking and smoking by a doctor, a woman who gave up her old house for a better view, and Kimura-san (Ep. 370) who wanted to stop improvising lyrics. Next was investigating local problem such as an overly thick matcha ice cream, a ryokan which having problems with broken appliances, and popular pose from Magician GO (Ep. 397). After that they checked on viewers' questions. The staff investigated a man who always uses binoculars from a rooftop near Shin-Imamiya, a man who failed 18 times at a driving exam, and a man who used a photo editor app to create a biker woman persona account. Lastly, the hosts tried the same photo editor app, just like in Ep. 397. (Source: Griffin Seannery at MyDramaList)